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Systematic Identification of Signal-Activated Stochastic Gene Regulation

Although much has been done to elucidate the biochemistry of signal transduction and gene regulatory pathways, it remains difficult to understand or predict quantitative responses. We integrate single-cell experiments with stochastic analyses, to identify predictive models of transcriptional dynamic...

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Detalhes bibliográficos
Main Authors: Neuert, Gregor, Munsky, Brian, Tan, Rui Zhen, Teytelman, Leonid, Khammash, Mustafa, van Oudenaarden, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751578/
https://ncbi.nlm.nih.gov/pubmed/23372015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1231456
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