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Oral antigen exposure in extreme early life in lambs influences the magnitude of the immune response which can be generated in later life

BACKGROUND: Previous investigations in newborn lambs determined that adenovirus-mediated expression of antigen to a localized region of the gut induced antigen-specific mucosal and systemic immunity. These experiments were limited in that the localized region of the gut to which antigen was introduc...

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Detalles Bibliográficos
Main Authors: Buchanan, Rachelle M, Mertins, Sonja, Wilson, Heather L
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751536/
https://ncbi.nlm.nih.gov/pubmed/23937675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1746-6148-9-160
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