8-hydroxy-2′-deoxyguanosine in colorectal adenocarcinoma – is it a result of oxidative stress?

BACKGROUND: 8-hydroxy-2′-deoxyguanosine (8-OHdG) is one of the most abundant oxidatively modified lesions in DNA and is a marker of the oxidative stress. 8-OHdG is a mutagenic lesion and it can mispair with adenine, causing G: C→T: A transversion. Our task was to determine the 8-OHdG level in patien...

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Bibliografiske detaljer
Main Authors: Płachetka, Anna, Adamek, Brygida, Strzelczyk, Joanna K., Krakowczyk, Łukasz, Migula, Paweł, Nowak, Przemysław, Wiczkowski, Andrzej
Format: Artigo
Sprog:Inglês
Udgivet: International Scientific Literature, Inc. 2013
Fag:
Clinical Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751519/
https://ncbi.nlm.nih.gov/pubmed/23963109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.883999
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