IGF2R Genetic Variants, Circulating IGF2 Concentrations and Colon Cancer Risk in African Americans and Whites

The Mannose 6 Phosphate/Insulin-like Growth Factor Receptor-2 (IGF2R) encodes a type-1 membrane protein that modulates availability of the potent mitogen, IGF2. We evaluated the associations between IGF2R non-synonymous genetic variants (c.5002G>A, Gly1619Arg(rs629849), and c.901C>G, Leu252Val...

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Autori principali: Hoyo, Cathrine, Murphy, Susan K., Schildkraut, Joellen M., Vidal, Adriana C., Skaar, David, Millikan, Robert C., Galanko, Joseph, Sandler, Robert S., Jirtle, Randy, Keku, Temitope
Natura: Artigo
Lingua:Inglês
Pubblicazione: IOS Press 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751395/
https://ncbi.nlm.nih.gov/pubmed/22377707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/DMA-2011-0865
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