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HDAC inhibitors in kidney development and disease

The discovery that histone deacetylase inhibitors (HDACis) can attenuate acute kidney injury (AKI)-mediated damage and reduce fibrosis in kidney disease models has opened the possibility of utilizing HDACis as therapeutics for renal injury. Studies to date have made it abundantly clear that HDACi tr...

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Bibliografische gegevens
Hoofdauteurs: Brilli, Lauren L., Swanhart, Lisa M., de Caestecker, Mark P., Hukriede, Neil A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer Berlin Heidelberg 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751322/
https://ncbi.nlm.nih.gov/pubmed/23052657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00467-012-2320-8
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