RABEX-5 plays an oncogenic role in breast cancer by activating MMP-9 pathway

BACKGROUND: RABEX-5, a guanine nucleotide exchange factor (GEF) for RAB-5, plays an important role in cell mobility and altered expression associated with tumor metastasis. This study aimed to investigate the role of RABEX-5 in proliferation and metastasis of breast cancer in vitro and ex vivo. METH...

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Hlavní autoři: Zhang, Xiang, Min, Jie, Wang, Yingjian, Li, Yan, Li, Hongzhong, Liu, Qiang, Liang, Xinjie, Mu, Peng, Li, Hongyuan
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751292/
https://ncbi.nlm.nih.gov/pubmed/23941575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-32-52
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