A Time-Resolved Fluorescence Resonance Energy Transfer Assay for High-Throughput Screening of 14-3-3 Protein–Protein Interaction Inhibitors

Protein–protein interaction networks mediate diverse biological processes by regulating various signaling hubs and clusters. 14-3-3 proteins, a family of phosphoserine/threonine-binding molecules, serve as major interaction hubs in eukaryotic cells and have emerged as promising therapeutic targets f...

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Detalhes bibliográficos
Main Authors: Du, Yuhong, Fu, Robert W., Lou, Bin, Zhao, Jing, Qui, Min, Khuri, Fadlo R., Fu, Haian
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2013
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751221/
https://ncbi.nlm.nih.gov/pubmed/23906346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/adt.2013.507
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