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4-Methylcoumarin Derivatives Inhibit Human Neutrophil Oxidative Metabolism and Elastase Activity

Increased neutrophil activation significantly contributes to the tissue damage in inflammatory illnesses; this phenomenon has motivated the search for new compounds to modulate their effector functions. Coumarins are natural products that are widely consumed in the human diet. We have evaluated the...

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Detalhes bibliográficos
Main Authors: Kabeya, Luciana M., Fuzissaki, Carolina N., Andrade, Micássio F., Azzolini, Ana Elisa C.S., Taleb-Contini, Silvia H., Vermelho, Roberta B., Lopes, João Luis C., Lucisano-Valim, Yara Maria
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751208/
https://ncbi.nlm.nih.gov/pubmed/23905650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jmf.2012.0184
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