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Ordered subset linkage analysis based on admixture proportion identifies new linkage evidence for alcohol dependence in African-Americans

Genetic heterogeneity could reduce the power of linkage analysis to detect risk loci for complex traits such as alcohol dependence (AD). Previously, we performed a genomewide linkage analysis for AD in African-Americans (AAs) (Gelernter et al., 2009). The power of that linkage analysis could have be...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Han, Shizhong, Gelernter, Joel, Kranzler, Henry R., Yang, Bao-Zhu
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751162/
https://ncbi.nlm.nih.gov/pubmed/23239122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-012-1255-2
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