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Cross-talk between GlcNAcylation and phosphorylation: roles in insulin resistance and glucose toxicity
O-linked β-N-acetylglucosamine (O-GlcNAc) is a dynamic posttranslational modification that, analogous to phosphorylation, cycles on and off serine and/or threonine hydroxyl groups. Cycling of O-GlcNAc is regulated by the concerted actions of O-GlcNAc transferase and O-GlcNAcase. GlcNAcylation is a n...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3751035/ https://ncbi.nlm.nih.gov/pubmed/18445751 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.90281.2008 |
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