H3 histamine receptor agonist inhibits biliary growth of BDL rats by downregulation of the cAMP-dependent PKA/ERK1/2/ELK-1 pathway

Histamine regulates many functions by binding to four histamine G-coupled receptor proteins (H1R, H2R, H3R and H4R). As H3R exerts their effects by coupling to Gα(i/o) proteins reducing adenosine 3′, 5′-monophosphate (cAMP) levels (a key player in the modulation of cholangiocyte hyperplasia/damage),...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Francis, Heather, Franchitto, Antonio, Ueno, Yoshiyuki, Glaser, Shannon, DeMorrow, Sharon, Venter, Julie, Gaudio, Eugenio, Alvaro, Domenico, Fava, Giammarco, Marzioni, Marco, Vaculin, Bradley, Alpini, Gianfranco
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751000/
https://ncbi.nlm.nih.gov/pubmed/17334413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.3700533
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados