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HRG-β1-driven ErbB3 signaling induces epithelial–mesenchymal transition in breast cancer cells
BACKGROUND: Heregulin (HRG; also known as neuregulin) is a ligand for ErbB3. One of its isotypes, HRG-β1, binds to ErbB3 and forms heterodimers with other ErbB family members, thereby enhancing the proliferation and tumorigenesis of breast cancer cells. HRG stimulation may contribute to the progress...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3750857/ https://ncbi.nlm.nih.gov/pubmed/23937725 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-383 |
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