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Engineered Pichia pastoris for enhanced production of S-adenosylmethionine

A genetically engineered strain of Pichia pastoris expressing S-adenosylmethionine synthetase gene from Saccharomyces cerevisiae under the control of AOX 1 promoter was developed. Induction of recombinant strain with 1% methanol resulted in the expression of SAM2 protein of ~ 42 kDa, whereas control...

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Autors principals: Kamarthapu, Venu, Ragampeta, Srinivas, Rao, Khareedu Venkateswara, Reddy, Vudem Dashavantha
Format: Artigo
Idioma:Inglês
Publicat: Springer 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750815/
https://ncbi.nlm.nih.gov/pubmed/23890127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2191-0855-3-40
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