Model for Concomitant Microdialysis Sampling of the Pons and Cerebral Cortex in Rhesus Macaques (Macaca mulatta)

Pediatric diffuse intrinsic pontine gliomas are aggressive brainstem tumors that fail to respond to treatment. We hypothesize that the protective features of the pons may hinder chemotherapeutic agents from entering pontine tissue compared with cortical brain tissue. To test this hypothesis, we deve...

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Autori principali: McCully, Cynthia M, Pastakia, Devang, Bacher, John, Thomas, Marvin L, Steffen-Smith, Emilie A, Saleem, Kadharbatcha, Murphy, Robert F, Walbridge, Stuart, Brinster, Lauren, Widemann, Brigitte C, Warren, Katherine E
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Association for Laboratory Animal Science 2013
Soggetti:
Nonhuman Primate Models
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750672/
https://ncbi.nlm.nih.gov/pubmed/24209972
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