Predictive Observation-Based Endpoint Criteria for Mice Receiving Total Body Irradiation

Total body irradiation of mice is a commonly used research technique; however, humane endpoints have not been clearly identified. This situation has led to the inconsistent use of various endpoints, including death. To address this issue, we refined a cageside observation-based scoring system specif...

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Main Authors: Nunamaker, Elizabeth A, Anderson, Robert J, Artwohl, James E, Lyubimov, Alexander V, Fortman, Jeffrey D
Format: Artigo
Sprog:Inglês
Udgivet: American Association for Laboratory Animal Science 2013
Fag:
Mouse Models
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750666/
https://ncbi.nlm.nih.gov/pubmed/24209966
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