Prognostic assessment of hypoxia and metabolic markers in cervical cancer using automated digital image analysis of immunohistochemistry

BACKGROUND: Hypoxia inducible factor-1 alpha (HIF-1α), induced by tumor hypoxia, regulates tumor cell metabolism and metastasis by up-regulation of c-Met, carbonic anhydrase 9 (CA9) and glucose transporter 1 (GLUT1). The prognostic significance of hypoxia and metabolic markers is not clearly defined...

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Bibliographische Detailangaben
Hauptverfasser: Kim, Bo Wook, Cho, Hanbyoul, Chung, Joon-Yong, Conway, Catherine, Ylaya, Kris, Kim, Jae-Hoon, Hewitt, Stephen M
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2013
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750663/
https://ncbi.nlm.nih.gov/pubmed/23927384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-11-185
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