Ursodeoxycholic acid counteracts celecoxib in reduction of duodenal polyps in patients with familial adenomatous polyposis: a multicentre, randomized controlled trial

BACKGROUND: Due to prophylactic colectomy, mortality in patients with familial adenomatous polyposis (FAP) has changed, with duodenal cancer currently being the main cause of death. Although celecoxib reduces duodenal polyp density in patients with FAP, its long-term use may increase the risk of car...

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Detalhes bibliográficos
Main Authors: van Heumen, Bjorn WH, Roelofs, Hennie MJ, Vink-Börger, M Elisa, Dekker, Evelien, Mathus-Vliegen, Elisabeth MH, Dees, Jan, Koornstra, Jan J, Langers, Alexandra MJ, Nagtegaal, Iris D, Kampman, Ellen, Peters, Wilbert HM, Nagengast,, Fokko M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750541/
https://ncbi.nlm.nih.gov/pubmed/23919274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1172-8-118
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