Anakinra pharmacokinetics in children and adolescents with systemic-onset juvenile idiopathic arthritis and autoinflammatory syndromes

BACKGROUND: Anakinra pharmacokinetics and pharmacodynamics were investigated in children and adolescents treated for systemic-onset juvenile idiopathic arthritis (SJIA) and autoinflammatory syndromes. METHODS: Anakinra was given subcutaneously at doses between 2 and 10 mg/kg (maximum 100 mg) per day...

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Autores principales: Urien, Saik, Bardin, Christophe, Bader-Meunier, Brigitte, Mouy, Richard, Compeyrot-Lacassagne, Sandrine, Foissac, Franz, Florkin, Benoît, Wouters, Carine, Neven, Bénédicte, Treluyer, Jean-Marc, Quartier, Pierre
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750485/
https://ncbi.nlm.nih.gov/pubmed/23915458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2050-6511-14-40
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