Ovarian Carcinoma: Quantitative Biexponential MR Imaging Relaxometry Reveals the Dynamic Recruitment of Ferritin-expressing Fibroblasts to the Angiogenic Rim of Tumors

PURPOSE: To quantitatively monitor the dynamic perivascular recruitment of ferritin heavy chain (FHC)–overexpressing fibroblasts to ovarian carcinoma xenografts by using R2 mapping and biexponential magnetic resonance (MR) relaxometry. MATERIALS AND METHODS: In vivo studies of female mice were appro...

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Hauptverfasser: Vandsburger, Moriel H., Radoul, Marina, Addadi, Yoseph, Mpofu, Senzeni, Cohen, Batya, Eilam, Raya, Neeman, Michal
Format: Artigo
Sprache:Inglês
Veröffentlicht: Radiological Society of North America, Inc. 2013
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750420/
https://ncbi.nlm.nih.gov/pubmed/23801774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1148/radiol.13122053
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