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FGFR3 has tumor suppressor properties in cells with epithelial phenotype
BACKGROUND: Due to frequent mutations in certain cancers, FGFR3 gene is considered as an oncogene. However, in some normal tissues, FGFR3 can limit cell growth and promote cell differentiation. Thus, FGFR3 action appears paradoxical. RESULTS: FGFR3 expression was forced in pancreatic cell lines. The...
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Main Authors: | , , , , , , , , , , , , , |
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פורמט: | Artigo |
שפה: | Inglês |
יצא לאור: |
BioMed Central
2013
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נושאים: | |
גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3750311/ https://ncbi.nlm.nih.gov/pubmed/23902722 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-12-83 |
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