FGFR3 has tumor suppressor properties in cells with epithelial phenotype

BACKGROUND: Due to frequent mutations in certain cancers, FGFR3 gene is considered as an oncogene. However, in some normal tissues, FGFR3 can limit cell growth and promote cell differentiation. Thus, FGFR3 action appears paradoxical. RESULTS: FGFR3 expression was forced in pancreatic cell lines. The...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lafitte, Marie, Moranvillier, Isabelle, Garcia, Stéphane, Peuchant, Evelyne, Iovanna, Juan, Rousseau, Benoit, Dubus, Pierre, Guyonnet-Dupérat, Véronique, Belleannée, Geneviève, Ramos, Jeanne, Bedel, Aurélie, de Verneuil, Hubert, Moreau-Gaudry, François, Dabernat, Sandrine
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2013
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750311/
https://ncbi.nlm.nih.gov/pubmed/23902722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-12-83
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