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Microarray profiling reveals suppressed interferon stimulated gene program in fibroblasts from scleroderma-associated interstitial lung disease

BACKGROUND: Interstitial lung disease is a major cause of morbidity and mortality in systemic sclerosis (SSc), with insufficiently effective treatment options. Progression of pulmonary fibrosis involves expanding populations of fibroblasts, and the accumulation of extracellular matrix proteins. Char...

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Detaylı Bibliyografya
Asıl Yazarlar: Lindahl, Gisela E, Stock, Carmel JW, Shi-Wen, Xu, Leoni, Patricia, Sestini, Piersante, Howat, Sarah L, Bou-Gharios, George, Nicholson, Andrew G, Denton, Christopher P, Grutters, Jan C, Maher, Toby M, Wells, Athol U, Abraham, David J, Renzoni, Elisabetta A
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750263/
https://ncbi.nlm.nih.gov/pubmed/23915349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-14-80
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