Microarray profiling reveals suppressed interferon stimulated gene program in fibroblasts from scleroderma-associated interstitial lung disease

BACKGROUND: Interstitial lung disease is a major cause of morbidity and mortality in systemic sclerosis (SSc), with insufficiently effective treatment options. Progression of pulmonary fibrosis involves expanding populations of fibroblasts, and the accumulation of extracellular matrix proteins. Char...

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Bibliografiske detaljer
Main Authors: Lindahl, Gisela E, Stock, Carmel JW, Shi-Wen, Xu, Leoni, Patricia, Sestini, Piersante, Howat, Sarah L, Bou-Gharios, George, Nicholson, Andrew G, Denton, Christopher P, Grutters, Jan C, Maher, Toby M, Wells, Athol U, Abraham, David J, Renzoni, Elisabetta A
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750263/
https://ncbi.nlm.nih.gov/pubmed/23915349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-14-80
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