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CTLA4-Ig (abatacept) therapy modulates T cell effector functions in autoantibody-positive rheumatoid arthritis patients

BACKGROUND: Rheumatoid arthritis is a chronic inflammatory disease with a strong MHC class II component and where many patients develop characteristic autoantibodies towards the noncoding amino acid citrulline. Such anti-citrullinated protein antibodies (ACPA) have recently been put forward as an in...

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Detalhes bibliográficos
Main Authors: Pieper, Jennifer, Herrath, Jessica, Raghavan, Sukanya, Muhammad, Khalid, Vollenhoven, Ronald van, Malmström, Vivianne
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750242/
https://ncbi.nlm.nih.gov/pubmed/23915385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-14-34
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