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REACTIN: Regulatory activity inference of transcription factors underlying human diseases with application to breast cancer

BACKGROUND: Genetic alterations of transcription factors (TFs) have been implicated in the tumorigenesis of cancers. In many cancers, alteration of TFs results in aberrant activity of them without changing their gene expression level. Gene expression data from microarray or RNA-seq experiments can c...

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Detalhes bibliográficos
Main Authors: Zhu, Mingzhu, Liu, Chun-Chi, Cheng, Chao
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750236/
https://ncbi.nlm.nih.gov/pubmed/23885756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-14-504
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