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Palladium-Catalyzed One-Step Synthesis of Isoindole-1,3-diones by Carbonylative Cyclization of o-Halobenzoates and Primary Amines

[Image: see text] The palladium-catalyzed aminocarbonylation of o-halobenzoates produces 2-substituted isoindole-1,3-diones in good yields. This methodology provides a good one-step approach to this important class of heterocycles and tolerates a variety of functional groups, including methoxy, alco...

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Détails bibliographiques
Auteurs principaux: Worlikar, Shilpa A., Larock, Richard C.
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750121/
https://ncbi.nlm.nih.gov/pubmed/18712929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo800936h
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