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Concentration Addition, Independent Action and Generalized Concentration Addition Models for Mixture Effect Prediction of Sex Hormone Synthesis In Vitro

Humans are concomitantly exposed to numerous chemicals. An infinite number of combinations and doses thereof can be imagined. For toxicological risk assessment the mathematical prediction of mixture effects, using knowledge on single chemicals, is therefore desirable. We investigated pros and cons o...

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Detalhes bibliográficos
Main Authors: Hadrup, Niels, Taxvig, Camilla, Pedersen, Mikael, Nellemann, Christine, Hass, Ulla, Vinggaard, Anne Marie
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750043/
https://ncbi.nlm.nih.gov/pubmed/23990906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070490
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