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Comparative Analysis of TGF-β/Smad Signaling Dependent Cytostasis in Human Hepatocellular Carcinoma Cell Lines

Hepatocellular carcinoma (HCC) is a major public health problem due to increased incidence, late diagnosis and limited treatment options. TGF-β is known to provide cytostatic signals during early stages of liver damage and regeneration, but exerts tumor promoting effects in onset and progression of...

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Detalhes bibliográficos
Main Authors: Dzieran, Johanna, Fabian, Jasmin, Feng, Teng, Coulouarn, Cédric, Ilkavets, Iryna, Kyselova, Anastasia, Breuhahn, Kai, Dooley, Steven, Meindl-Beinker, Nadja M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750029/
https://ncbi.nlm.nih.gov/pubmed/23991075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072252
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