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Evidence for Sigma Factor Competition in the Regulation of Alginate Production by Pseudomonas aeruginosa

Alginate overproduction, or mucoidy, plays an important role in the pathogenesis of P. aeruginosa lung infection in cystic fibrosis (CF). Mucoid strains with mucA mutations predominantly populate in chronically-infected patients. However, the mucoid strains can revert to nonmucoidy in vitro through...

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Detalhes bibliográficos
Main Authors: Yin, Yeshi, Withers, T. Ryan, Wang, Xin, Yu, Hongwei D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750012/
https://ncbi.nlm.nih.gov/pubmed/23991093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072329
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