The Retinoic Acid-Metabolizing Enzyme Cyp26b1 Regulates CD4 T Cell Differentiation and Function

The vitamin A metabolite retinoic acid (RA) has potent immunomodulatory properties that affect T cell differentiation, migration and function. However, the precise role of RA metabolism in T cells remains unclear. Catabolism of RA is mediated by the Cyp26 family of cytochrome P450 oxidases. We exami...

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Main Authors: Chenery, Alistair, Burrows, Kyle, Antignano, Frann, Underhill, T. Michael, Petkovich, Martin, Zaph, Colby
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750006/
https://ncbi.nlm.nih.gov/pubmed/23991089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072308
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