PI3K p110γ Deletion Attenuates Murine Atherosclerosis by Reducing Macrophage Proliferation but Not Polarization or Apoptosis in Lesions

Atherosclerosis is an inflammatory disease regulated by infiltrating monocytes and T cells, among other cell types. Macrophage recruitment to atherosclerotic lesions is controlled by monocyte infiltration into plaques. Once in the lesion, macrophage proliferation in situ, apoptosis, and differentiat...

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Detalhes bibliográficos
Main Authors: Zotes, Teresa M., Arias, Cristina F., Fuster, José J., Spada, Roberto, Pérez-Yagüe, Sonia, Hirsch, Emilio, Wymann, Matthias, Carrera, Ana C., Andrés, Vicente, Barber, Domingo F.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750002/
https://ncbi.nlm.nih.gov/pubmed/23991137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072674
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