Effect of PEEP and Tidal Volume on Ventilation Distribution and End-Expiratory Lung Volume: A Prospective Experimental Animal and Pilot Clinical Study

INTRODUCTION: Lung-protective ventilation aims at using low tidal volumes (V(T)) at optimum positive end-expiratory pressures (PEEP). Optimum PEEP should recruit atelectatic lung regions and avoid tidal recruitment and end-inspiratory overinflation. We examined the effect of V(T) and PEEP on ventila...

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Main Authors: Zick, Günther, Elke, Gunnar, Becher, Tobias, Schädler, Dirk, Pulletz, Sven, Freitag-Wolf, Sandra, Weiler, Norbert, Frerichs, Inéz
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750001/
https://ncbi.nlm.nih.gov/pubmed/23991138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072675
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