Aspergillus Galactosaminogalactan Mediates Adherence to Host Constituents and Conceals Hyphal β-Glucan from the Immune System

Aspergillus fumigatus is the most common cause of invasive mold disease in humans. The mechanisms underlying the adherence of this mold to host cells and macromolecules have remained elusive. Using mutants with different adhesive properties and comparative transcriptomics, we discovered that the gen...

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Detalhes bibliográficos
Main Authors: Gravelat, Fabrice N., Beauvais, Anne, Liu, Hong, Lee, Mark J., Snarr, Brendan D., Chen, Dan, Xu, Wenjie, Kravtsov, Ilia, Hoareau, Christopher M. Q., Vanier, Ghyslaine, Urb, Mirjam, Campoli, Paolo, Al Abdallah, Qusai, Lehoux, Melanie, Chabot, Josée C., Ouimet, Marie-Claude, Baptista, Stefanie D., Fritz, Jörg H., Nierman, William C., Latgé, Jean Paul, Mitchell, Aaron P., Filler, Scott G., Fontaine, Thierry, Sheppard, Donald C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749958/
https://ncbi.nlm.nih.gov/pubmed/23990787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003575
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