Combining Quantitative Genetic Footprinting and Trait Enrichment Analysis to Identify Fitness Determinants of a Bacterial Pathogen

Strains of Extraintestinal Pathogenic Escherichia c oli (ExPEC) exhibit an array of virulence strategies and are a major cause of urinary tract infections, sepsis and meningitis. Efforts to understand ExPEC pathogenesis are challenged by the high degree of genetic and phenotypic variation that exist...

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Main Authors: Wiles, Travis J., Norton, J. Paul, Russell, Colin W., Dalley, Brian K., Fischer, Kael F., Mulvey, Matthew A.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2013
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749937/
https://ncbi.nlm.nih.gov/pubmed/23990803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003716
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