Increased Occurrence of Valproic Acid-Induced Hyperammonemia in Carriers of T1405N Polymorphism in Carbamoyl Phosphate Synthetase 1 Gene

Numerous cases of severe and life-threatening hyperammonemia (HA) related to the treatment of epileptic seizures with valproic acid (VPA) have been previously reported in the medical literature. The aim of this prospective, multicenter study was to verify the putative association between T1405 polym...

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Detalhes bibliográficos
Main Authors: Janicki, Piotr K., Bezinover, Dmitri, Postula, Marek, Thompson, Robert S., Acharya, Jayant, Acharya, Vinita, McNew, Cathy, Bowman, J. Daniel, Kurkowska-Jastrzebska, Iwona, Mirowska-Guzel, Dagmara
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749598/
https://ncbi.nlm.nih.gov/pubmed/23997965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/261497
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