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Evolutionary game theory of growth factor production: implications for tumour heterogeneity and resistance to therapies

BACKGROUND: Tumour heterogeneity is documented for many characters, including the production of growth factors, one of the hallmarks of cancer. What maintains heterogeneity remains an open question that has implications for diagnosis and treatment, as drugs that target growth factors are susceptible...

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Detalhes bibliográficos
Autor principal: Archetti, M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749558/
https://ncbi.nlm.nih.gov/pubmed/23922110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.336
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