Developmental GnRH Signaling Is Not Required for Sexual Differentiation of Kisspeptin Neurons but Is Needed for Maximal Kiss1 Gene Expression in Adult Females

Kisspeptin, encoded by Kiss1, stimulates reproduction. In rodents, one Kiss1 population resides in the hypothalamic anterior ventral periventricular nucleus and neighboring rostral periventricular nucleus (AVPV/PeN). AVPV/PeN Kiss1 neurons are sexually dimorphic (greater in females), yet the mechani...

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Autores principales: Kim, Joshua, Tolson, Kristen P., Dhamija, Sangeeta, Kauffman, Alexander S.
Formato: Artigo
Lenguaje:Inglês
Publicado: Endocrine Society 2013
Materias:
Neuroendocrinology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749477/
https://ncbi.nlm.nih.gov/pubmed/23825121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2013-1271
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