Tetrahydrobiopterin Has a Glucose-Lowering Effect by Suppressing Hepatic Gluconeogenesis in an Endothelial Nitric Oxide Synthase–Dependent Manner in Diabetic Mice

Endothelial nitric oxide synthase (eNOS) dysfunction induces insulin resistance and glucose intolerance. Tetrahydrobiopterin (BH(4)) is an essential cofactor of eNOS that regulates eNOS activity. In the diabetic state, BH(4) is oxidized to 7,8-dihydrobiopterin, which leads to eNOS dysfunction owing...

全面介紹

Na minha lista:
書目詳細資料
Main Authors: Abudukadier, Abulizi, Fujita, Yoshihito, Obara, Akio, Ohashi, Akiko, Fukushima, Toru, Sato, Yuichi, Ogura, Masahito, Nakamura, Yasuhiko, Fujimoto, Shimpei, Hosokawa, Masaya, Hasegawa, Hiroyuki, Inagaki, Nobuya
格式: Artigo
語言:Inglês
出版: American Diabetes Association 2013
主題:
Original Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749361/
https://ncbi.nlm.nih.gov/pubmed/23649519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-1242
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍