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Plasma Levels of Soluble Urokinase-Type Plasminogen Activator Receptor Associate with the Clinical Severity of Acute Puumala Hantavirus Infection

OBJECTIVES: Urokinase-type plasminogen activator receptor is a multifunctional glycoprotein, the expression of which is increased during inflammation. It is known to bind to β(3)-integrins, which are elementary for the cellular entry of hantaviruses. Plasma soluble form of the receptor (suPAR) level...

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Detalhes bibliográficos
Main Authors: Outinen, Tuula K., Tervo, Laura, Mäkelä, Satu, Huttunen, Reetta, Mäenpää, Niina, Huhtala, Heini, Vaheri, Antti, Mustonen, Jukka, Aittoniemi, Janne
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749226/
https://ncbi.nlm.nih.gov/pubmed/23990945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071335
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