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Cryptococcosis-IRIS is Associated With Lower Cryptococcus-specific IFN-γ Responses Before Antiretroviral Therapy but Not Higher T-Cell Responses During Therapy

Background. Cryptococcosis-associated immune reconstitution inflammatory syndrome (C-IRIS) may be driven by aberrant T-cell responses against cryptococci. We investigated this in human immunodeficiency virus (HIV)–infected patients with treated cryptococcal meningitis (CM) commencing combination ant...

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Bibliographische Detailangaben
Hauptverfasser: Chang, Christina C., Lim, Andrew, Omarjee, Saleha, Levitz, Stuart M., Gosnell, Bernadett I., Spelman, Tim, Elliott, Julian H., Carr, William H., Moosa, Mohamed-Yunus S., Ndung'u, Thumbi, Lewin, Sharon R., French, Martyn A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2013
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749010/
https://ncbi.nlm.nih.gov/pubmed/23766525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jit271
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