Wnt3a Reestablishes Osteogenic Capacity to Bone Grafts from Aged Animals

BACKGROUND: Age-related fatty degeneration of the bone marrow contributes to delayed fracture-healing and osteoporosis-related fractures in the elderly. The mechanisms underlying this fatty change are unknown, but they may relate to the level of Wnt signaling within the aged marrow cavity. METHODS:...

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Hlavní autoři: Leucht, Philipp, Jiang, Jie, Cheng, Du, Liu, Bo, Dhamdhere, Girija, Fang, Mark Yang, Monica, Stefanie D., Urena, Jonathan J., Cole, Whitney, Smith, Lane R., Castillo, Alesha B., Longaker, Michael T., Helms, Jill A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Journal of Bone and Joint Surgery, Inc. 2013
Témata:
Scientific Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3748990/
https://ncbi.nlm.nih.gov/pubmed/23864176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2106/JBJS.L.01502
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