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Specific gut commensal flora locally alters T cell tuning to endogenous ligands

Differences in gut commensal flora can dramatically influence autoimmune responses, but the mechanisms behind this are still unclear. We report, in a Th1 cell-driven murine model of autoimmune arthritis, that specific gut commensals, such as segmented filamentous bacteria, have the ability to modula...

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Detalhes bibliográficos
Main Authors: Chappert, Pascal, Bouladoux, Nicolas, Naik, Shruti, Schwartz, Ronald H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3748804/
https://ncbi.nlm.nih.gov/pubmed/23809163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2013.06.005
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