Phase II evaluation of Dasatinib in the treatment of recurrent or persistent epithelial ovarian or primary peritoneal carcinoma: A Gynecologic Oncology Group study

OBJECTIVE: Preclinical data suggest an important role for the sarcoma proto-oncogene tyrosine kinase (SRC) in the oncogenesis of epithelial ovarian cancer (EOC) or primary peritoneal carcinoma (PPC). The Gynecologic Oncology Group (GOG) conducted a Phase II trial to evaluate the efficacy and safety...

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Autores principales: Schilder, Russell J., Brady, William E., Lankes, Heather A., Fiorica, James V., Shahin, Mark S., Zhou, Xun C., Mannel, Robert S., Pathak, Harsh B., Hu, Wei, Alpaugh, R. Katherine, Sood, Anil K., Godwin, Andrew K.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3748717/
https://ncbi.nlm.nih.gov/pubmed/22710075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2012.06.009
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