The β3 Subunit Contributes to Vascular Calcium Channel Upregulation and Hypertension in Angiotensin II-infused C57BL/6 Mice

Voltage-gated L-type Ca(2+) (Ca(v)1.2) channels in vascular smooth muscle cells (VSMCs) are a predominant Ca(2+) influx pathway that mediates arterial tone. Channel biogenesis is accomplished when the pore-forming α(1C) subunit co-assembles with regulatory Ca(v)β subunits intracellularly, and the mu...

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Detalhes bibliográficos
Main Authors: Kharade, Sujay V., Sonkusare, Swapnil K., Srivastava, Anup K., Thakali, Keshari M., Fletcher, Terry W., Rhee, Sung W., Rusch, Nancy J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3748590/
https://ncbi.nlm.nih.gov/pubmed/23129698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.112.197863
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