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Increasing Vascularity to Improve Healing of a Segmental Defect of the Rat Femur

BACKGROUND: Segmental bone loss remains a challenging clinical problem. A frequent mitigating factor is inadequate blood supply. Small molecules that activate the hypoxia inducible factor pathway (HIF) can be used to stimulate angiogenesis. We investigated an approach to promote healing using angiog...

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Detalhes bibliográficos
Main Authors: Stewart, Rena, Goldstein, Jessica, Eberhardt, Alan, Chu, Tien-Min Gabriel, Gilbert, Shawn
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3748583/
https://ncbi.nlm.nih.gov/pubmed/21738061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/BOT.0b013e31822588d8
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