Identification of the Tetraspanin CD82 as a New Barrier to Xenotransplantation

Significant immunological obstacles are to be negotiated before xenotransplantation becomes a clinical reality. An initial rejection of transplanted vascularized xenograft is attributed to Galα1,3Galβ1,4GlcNAc-R (Galα1,3-Gal)–dependent and –independent mechanisms. Hitherto, no receptor molecule has...

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Main Authors: Saleh, Soad M., Parhar, Ranjit S., Al-Hejailan, Reem S., Bakheet, Razan H., Khaleel, Hala S., Khalak, Hanif G., Halees, Anason S., Zaidi, Marya Z., Meyer, Brian F., Yung, Gisella P., Seebach, Jörg D., Conca, Walter, Khabar, Khalid S., Collison, Kate S., Al-Mohanna, Futwan A.
Format: Artigo
Jezik:Inglês
Izdano: AAI 2013
Teme:
Transplantation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3748337/
https://ncbi.nlm.nih.gov/pubmed/23872050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300601
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