Identification of the Tetraspanin CD82 as a New Barrier to Xenotransplantation

Significant immunological obstacles are to be negotiated before xenotransplantation becomes a clinical reality. An initial rejection of transplanted vascularized xenograft is attributed to Galα1,3Galβ1,4GlcNAc-R (Galα1,3-Gal)–dependent and –independent mechanisms. Hitherto, no receptor molecule has...

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Detalhes bibliográficos
Main Authors: Saleh, Soad M., Parhar, Ranjit S., Al-Hejailan, Reem S., Bakheet, Razan H., Khaleel, Hala S., Khalak, Hanif G., Halees, Anason S., Zaidi, Marya Z., Meyer, Brian F., Yung, Gisella P., Seebach, Jörg D., Conca, Walter, Khabar, Khalid S., Collison, Kate S., Al-Mohanna, Futwan A.
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2013
Assuntos:
Transplantation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3748337/
https://ncbi.nlm.nih.gov/pubmed/23872050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300601
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