STIM1 and Orai1 Mediate CRAC Channel Activity and are Essential for Human Glioblastoma Invasion

The Ca(2+) sensor stromal interacting molecule 1 (STIM1) and the Ca(2+) channel Orai1 mediate the ubiquitous store-operated Ca(2+) entry (SOCE) pathway activated by depletion of internal Ca(2+) stores and mediated through the highly Ca(2+) selective, Ca(2+) release-activated Ca(2+) (CRAC) current. F...

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Main Authors: Motiani, Rajender K., Hyzinski-García, María C., Zhang, Xuexin, Henkel, Matthew M., Abdullaev, Iskandar F., Kuo, Yu-Hung, Matrougui, Khalid, Mongin, Alexander A., Trebak, Mohamed
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3748246/
https://ncbi.nlm.nih.gov/pubmed/23515871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-013-1254-8
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