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An animal model of oxaliplatin-induced cold allodynia reveals a crucial role for Na(v)1.6 in peripheral pain pathways

Cold allodynia, pain in response to cooling, occurs during or within hours of oxaliplatin infusion and is thought to arise from a direct effect of oxaliplatin on peripheral sensory neurons. To characterize the pathophysiological mechanisms underlying acute oxaliplatin-induced cold allodynia, we esta...

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Détails bibliographiques
Auteurs principaux: Deuis, Jennifer R, Zimmermann, Katharina, Romanovsky, Andrej A, Possani, Lourival D, Cabot, Peter J, Lewis, Richard J, Vetter, Irina
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3748219/
https://ncbi.nlm.nih.gov/pubmed/23711479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2013.05.032
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