20-hydroxyecdysone upregulates Atg genes to induce autophagy in the Bombyx fat body

Autophagy is finely regulated at multiple levels and plays crucial roles in development and disease. In the fat body of the silkworm, Bombyx mori, autophagy occurs and Atg gene expression peaks during the nonfeeding molting and pupation stages when the steroid hormone (20-hydroxyecdysone; 20E) is hi...

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Bibliographic Details
Main Authors: Tian, Ling, Ma, Li, Guo, Enen, Deng, Xiaojuan, Ma, Sanyuan, Xia, Qingyou, Cao, Yang, Li, Sheng
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2013
Subjects:
Basic Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3748190/
https://ncbi.nlm.nih.gov/pubmed/23674061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.24731
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