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An angiogenic role for the α5β1 integrin in promoting endothelial cell proliferation during cerebral hypoxia

Fibronectin is a critical regulator of vascular modelling, both in development and in the adult. In the hypoxic adult central nervous system (CNS), fibronectin is induced on angiogenic vessels, and endothelial cells show strong induction of the two fibronectin receptors α5β1 and αvβ3 integrins. In a...

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Main Authors: Li, Longxuan, Welser-Alves, Jennifer, van der Flier, Arjan, Boroujerdi, Amin, Hynes, Richard O., Milner, Richard
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3748139/
https://ncbi.nlm.nih.gov/pubmed/22721769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2012.06.005
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